5 Findings on ALIF Clinical Effectiveness

Written by  Laura Dyrda

An article published in Spine examines the effectiveness of anterior lumbar interbody fusion for degenerative disc disease in the lumbar spine.

 The researchers reviewed a consecutive series of patients who had one- and two-level ALIF between 2005 and 2010 using recombinant human bone morphogenetic protein-2. Here are five findings from the study:

1. Patients reported significant Oswestry Disability Index and visual analogue scale improvements two years after surgery. A 2012 study published in the Journal of Spinal Disorders and Techniques showed that VAS and ODI improved significantly overtime for single-level ALIF and anteroposterior lumbar fusion, but patient satisfaction consistently ranked higher in the ALIF group. The study authors suggested performing a standalone ALIF in cases with single-level DDD.

2. The two-year postoperative disc height was significantly greater than the preoperative disc height at the fused level. A 2011 study examined whether disc space height of the fused segment affects adjacent degeneration in ALIF, finding the decreased disc space height adversely aggravated the adjacent segment degeneration.




Josh Sandberg

Josh Sandberg is the President of Ortho Sales Partners and Partner for The De Angelis Group. He also serves as Co-Founder and Editor of OrthoSpineNews.

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