Compared with patients who underwent total knee replacement, patients who underwent unicompartmental knee replacement experienced a significantly higher risk of revision/reoperation, according to study results.
Researchers compared matched patients undergoing TKR and unicompartmental knee replacement (UKR) in the National Joint Registry for England and Wales and linked data for multiple potential confounders from the National Health Service Hospital Episode Statistics database. Regression models were used to compare outcomes, including rates of revision, revision/reoperation, complications, readmission, mortality and length of stay.
On the basis of propensity score, researchers matched 25,334 UKRs to 75,996 TKRs. At 8 years, study results showed a worse implant survival for both revision and revision/reoperation among patients who underwent UKRs vs. TKRs. However, mortality was significantly higher for TKR at all time points compared with UKR, according to the researchers.
Additionally, length of stay, complications and rate of readmission were all higher among patients who underwent TKR.
Disclosures: Pandit is a paid speaker for Biomet. Murray receives royalties related to the Oxford UKR and is a paid consultant for Biomet. Judge received honoraria from Roche, held advisory board positions for Anthera and received consortium research greats from Servier.